Department of Clinical Biochemistry

About Department

AN OVERVIEW:

The Clinical Biochemistry Department is one of the important basic sciences departments of the College of Medicine, King Khalid University. The Department teaches clinical and applied biochemistry courses to medical students and other Health Sciences Colleges (Dentistry and Pharmacy) at both undergraduate and post graduate levels. Faculty members are actively involved in reesearch in Clinical Biochemistry, Molecular Biology, and Genetic Engineering.

VISION, MISSION AND GOALS:

VISION: The Clinical Biochemistry department Strives for excellence in teaching, medical research, and community service utilizing the Department's faculty staff expertise and research.

MISSION: Preparing graduates at a high level of scientific skills and laboratory experience to help in understanding the basis of biochemical biological processes within the human body in health and disease, and to enable in the continuous progress in the field of health sciences in all medical fields.

GOALS:

Efficiency in teaching medical students and other colleges such as Dentistry, and Pharmacy the theoretical and practical aspects of biochemical and biomedical specialties related to clinical biochemistry.
Active participation in conducting research concentrating on studying clinical topics, community health problems, and endemic diseases, at national, regional, and international levels.
Publication of the results of research in local, regional and international periodicals, and presenting them at conferences.
Departmental participation in fields of community service and environment.
Performing general, specialized, and confirmatory diagnostic laboratory tests.

The department teaches MBC226 and MBC227 and MBC534 courses for the MBBS program. In addition, the department teaches biochemistry courses for the Pharmacy [MBC223 MBC228] and Dentistry [MBC224 MBC225] colleges.

Department Committees

The Department, represented by its teaching staff members, has been participating in several committees of the College and the University, as well as forming a number of permanent and temporary committees at the Department:

1. College and University level:

· College Academic Affairs Office

· College Academic Guidance Committee

· College Postgraduate Studies Committee for Basic Sciences

· College Stem Cell Research Committee

· College Research Ethics Committee

· Committee for preparing a biostatistics curriculum for postgraduate students at the faculty’s basic sciences departments

· Committee for organizing the College's Annual Scientific Research Day event

· College E-learning Committee

· Committee for developing the University's Website

2. Department level:

· Academic Timetable Preparation

· Curricula Evaluation Committee

· Scientific Research Committee

· Teaching Staff Member Promotion Committee

· Committee for Auditing and Revising Examination Results

· Committee for the Master's Degree in Clinical Biochemistry

· Committee for looking at ways to bring Saudis with competencies to work at the Department.

Head of the Department of Clinical Biochemistry

Head of the Department of Clinical Biochemistry

Dr Muhammed Alshehri

Nephrologist and Internal Medicine

College of Medicine

Department of Clinical Biochemistry

P.O. Box: 641, Abha

Telephone: 07 241 7xxx

E-mail: maabdulaziz@kku.edu.sa

Scientific Certification

Consultant in Internal Medicine and Nephrology
American Board Certified in Internal Medicine and Nephrology
Head of the Academic Office at the College of Medicine
Member of the Institutional Review Board (IRB) Committee for Saudi German Hospital - Aseer
Member of the Nephrology Fellowship Training Program at Aseer Central Hospital

Program, Courses and Faculty

Programs and Courses:

The department teaches 8 courses to the students of the College of Medicine,

College of Dentistry, and College of Pharmacy:

1. Courses for College of Medicine students:

SN	Course Name	Course Code	Level	Credit Hours
1	Biochemistry 1	MBC 226	L3	4(3+1)
2	Biochemistry 2	MBC 227	L4	4(3+1)
3	Applied Molecular Medicine	MBC 534	L10	2(2+0)

2. Integrated Curriculum Courses under department’s coordination

SN	Course Name	Course Code	Year	Credit Hours
1	Metabolism and Nutrition	MBC2371	2	4
2	Molecular Medicine	MBC3273	3	2
3	Endocrine System	END 3672	3	8
4	Human Genetics (Elective)	GEN 4235	4	2

3. Integrated Curriculum Courses under department’s shared teaching

SN	Course Name	Course Code	Year	Credit Hours
1	Essential Foundation Course-1	FOU 2451	2	5
2	Growth and Development	GRD 2352	2	4
3	Musculoskeletal & Integumentary Systems	MUS 2653	2	8
4	Gastrointestinal System	GIT 2654	2	8
5	Cardiovascular System	CVR 2681	2	8
6	Reproductive System	GNT 3683	3	8
7	Renal System	REN 3684	3	10
8	Hematopoietic & Lymphatic Systems	HEM 3752	3	8
9	Neuroscience & Special Senses	NES 3655		4
10	Training & Career Preparation Skills	COMM 0401

4.. Courses for College of Dentistry, Nursing and Pharmacy students:

SN	Course Name	Course Code	Level	Credit Hours
1	Pharmacy	MBC 223	L3	3(2+1)
2	Pharmacy	MBC 228	L4	3(2+1)
3	Dentistry	MBC 224	L3	3(2+1)
4	Dentistry	MBC 225	L4	3(2+1)

Research

The Research provides the basic feed for academic knowledge across all academic departments. Research provides depth in the knowledge of a given area of exploration. The Biochemistry department has been involved in many aspects of research fields.

Selected Research Papers Published by Biochem Faculty

Clinical and biochemical predictors of nonalcoholic fatty liver disease among type 2 diabetes mellitus patients at primary health care level in south western Saudi Arabia. Diagnostics, 10(10), 809 (Al Humayed et al., 2020).
In-silico and in-vitro studies revealed alpha-amyrin as a potent inhibitor of TLR2 for the therapeutics of bacterial infection and sepsis. Cellular and Molecular Biology, 70(6), 97–107 (Thoraya A- Elgadir, 2024).
Pulsatillic acid as a potential inhibitor of protein kinase C-alpha in non-small cell lung cancer. Cellular and Molecular Biology, 70(7), 49–57 (Basiouny Basiouny El-Gamal, 2024).
Chen, Y. K., Mohamed, A. H., Amer Alsaiari, A., Olegovich Bokov, D., Patel, A., Al Abdulmonem, W., Shafie, A., Adnan Ashour, A., Azhar Kamal, M., Ahmad, F., & Ahmad, I. (2024). The role of mesenchymal stem cells in the treatment and pathogenesis of psoriasis. Cytokine, 182*, 156699 (Chen et al., 2024).
Structural dynamics of PCSK9 loss-of-function variants: implications for LDL cholesterol regulation and cardiovascular risk. PubMed, PMID: 41456255 (Tarique et al., 2025).
Impact of gold nanoparticle exposure on the development of pancreas and kidney: Dose-dependent oxidative stress, miRNA expression and Nrf2/ARE signalling. International Immunopharmacology, 150*, 114409 (Al-Zahrani & Shar, 2025).
Natural products in prostate cancer: Crosstalk among the gut microbiome, androgen receptor signaling, and epigenetic regulation. Preprints, doi:10.20944/preprints202605.1526.v1 (Mir et al., 2026).
Assessment of biochemical risk markers and correlation of serum electrolytes with glycated hemoglobin in type 2 diabetes mellitus. Biomedical Research, 27(4), 1011–1016.
Metabolic and anti-inflammatory properties of bioactive phytochemicals in modern clinical biochemistry. Journal of Clinical Biochemistry and Nutrition, 60(2), 85–92.
Evaluating the correlation between fasting blood glucose, HbA1c, and lipid profile parameters in Saudi metabolic syndrome patients. Journal of Medical Biochemistry, 37(3), 214–222.
Changes in serum trace elements and antioxidant enzyme status in patients with chronic renal failure in the Asir region. Saudi Journal of Biological Sciences, 26(7), 1432–1438.
Diagnostic value of serum adenosine deaminase activity and total protein levels in tuberculous pleural effusion. Journal of Clinical and Diagnostic Research, 14(5), BC01–BC05.
Identification of therapeutic targets in hepatic steatosis through differential serum proteomic and biochemical screening. Annals of Clinical Biochemistry, 58(4), 312–321.
The role of pro-inflammatory cytokines and serum ferritin levels as prognostic biomarkers in type 2 diabetes complications. Endocrine Research, 46(2), 77–85.
Evaluation of altered renal function parameters and calcium-phosphate homeostasis in diabetic nephropathy patients in Abha. Journal of Diabetes and its Complications, 36(8), 108244.
Molecular insights into the cardioprotective effects of thymoquinone via modulation of oxidative stress markers in experimental models. Biomedicine & Pharmacotherapy, 159*, 114210.
Biochemical assessment of serum vitamin D, zinc, and magnesium concentrations in relation to insulin resistance among Saudi adolescents. Nutrients, 15(11), 2541.
Association between liver enzymes, high-sensitivity C-reactive protein, and cardiovascular risk indices in non-alcoholic fatty liver disease. Disease Markers, 2024*, Art ID 6698124.
The protective role of green tea extract against cisplatin-induced nephrotoxicity: A biochemical and molecular profiling study. Journal of Biochemical and Molecular Toxicology, 39(2), e23611.

Staff and Faculty List

Name	Nationality	Academic Rank	Office phone	KKU Username
MALE SECTION
Muhammed Abdullah AlShehri	Saudi	Assistant Professor (HOD)	7991	maabdulaziz
Mohamed Abd Ellatif	Egyptian	Professor	7865	mabdellatif
Waleed Niazy Hassan	Egyptian	Professor	7867	wnhassan
Salah Ahmed Sheweita	Egyptian	Professor	7867	ssheweita
Khalid Ali Nasif Mohamed Ismail	Egyptian	Associate Professor	8472	kismail
Mohammed Amanullah	Indian	Associate Professor	7863	maman
Ayaz Khurram Mallick	Indian	Associate Professor		amallick
Ayyub Ali Patel	British UK	Associate Professor	7870	ayyub
Imad M. Al-Ghawanmeh	Jordanian	Lecturer	8295	alghawanmeh
Mohammed Babiker Abdelrouf	Sudanese	Assistant Professor	4427	mbabkr
Saif Abdullah Saif Shahrani	Saudi	Biochem Lab. Tech. (Dept. Secretary)	7878	saab.alshahrani
FEMALE SECTION	Nationality	Academic Rank	Office phone	KKU Username
Rehan Munir Youssif Soliman	Egyptian	Associate Professor	2513	rsoliman
Noora Saeed Khamees Al Zahrani	Saudi	Assistant Professor	2513	nalzahrani
Muniera Yousif Mohi Eldeen	Sudanese	Lecturer	2513	myousof
Marwa Esmaeel Saeed	Sudanese	Lecturer	2513	misaeed
Safa Hassan Umer	Sudanese	Lecturer	2513	shasn

Community Services

The department's role extends to participation in community service and public health education programs and seminars, as well as participation in academic seminars in secondary schools to provide professional medical information.

The department also welcomes junior high school students and familiarizes them with the parts of the human body.

Our aim is to support the training of young residents and doctors. There are courses for training in specific surgical techniques. In addition, we help develop and test new technologies and surgical instruments, as well as newly invented prostheses and implants. We also support training for paramedical groups such as physical therapy and medical technology companies.

We organize clinical courses in almost every medical field: Emergency Medicine, Infiltration Course, Neurosurgery, Otolaryngology, Plastic Surgery, Orthopedic Surgery, Cardiovascular Surgery, Visceral Surgery, Gynecology, Robotic Surgery, Intensive Care Medicine, Pedal Surgery, Anesthesia Care, Intensive Care Medicine.